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Three-dimensional and multienergy gamma-ray simultaneous imaging by using a Si/CdTe Compton camera.

Identifieur interne : 000316 ( Main/Exploration ); précédent : 000315; suivant : 000317

Three-dimensional and multienergy gamma-ray simultaneous imaging by using a Si/CdTe Compton camera.

Auteurs : RBID : pubmed:23418002

English descriptors

Abstract

To develop a silicon (Si) and cadmium telluride (CdTe) imaging Compton camera for biomedical application on the basis of technologies used for astrophysical observation and to test its capacity to perform three-dimensional (3D) imaging.

DOI: 10.1148/radiol.13121194
PubMed: 23418002

Links toward previous steps (curation, corpus...)


Le document en format XML

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<title xml:lang="en">Three-dimensional and multienergy gamma-ray simultaneous imaging by using a Si/CdTe Compton camera.</title>
<author>
<name sortKey="Suzuki, Yoshiyuki" uniqKey="Suzuki Y">Yoshiyuki Suzuki</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Radiation Oncology, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Radiation Oncology, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Yamaguchi, Mitsutaka" uniqKey="Yamaguchi M">Mitsutaka Yamaguchi</name>
</author>
<author>
<name sortKey="Odaka, Hirokazu" uniqKey="Odaka H">Hirokazu Odaka</name>
</author>
<author>
<name sortKey="Shimada, Hirofumi" uniqKey="Shimada H">Hirofumi Shimada</name>
</author>
<author>
<name sortKey="Yoshida, Yukari" uniqKey="Yoshida Y">Yukari Yoshida</name>
</author>
<author>
<name sortKey="Torikai, Kota" uniqKey="Torikai K">Kota Torikai</name>
</author>
<author>
<name sortKey="Satoh, Takahiro" uniqKey="Satoh T">Takahiro Satoh</name>
</author>
<author>
<name sortKey="Arakawa, Kazuo" uniqKey="Arakawa K">Kazuo Arakawa</name>
</author>
<author>
<name sortKey="Kawachi, Naoki" uniqKey="Kawachi N">Naoki Kawachi</name>
</author>
<author>
<name sortKey="Watanabe, Shigeki" uniqKey="Watanabe S">Shigeki Watanabe</name>
</author>
<author>
<name sortKey="Takeda, Shin Ichiro" uniqKey="Takeda S">Shin'ichiro Takeda</name>
</author>
<author>
<name sortKey="Ishikawa, Shin Nosuke" uniqKey="Ishikawa S">Shin-nosuke Ishikawa</name>
</author>
<author>
<name sortKey="Aono, Hiroyuki" uniqKey="Aono H">Hiroyuki Aono</name>
</author>
<author>
<name sortKey="Watanabe, Shin" uniqKey="Watanabe S">Shin Watanabe</name>
</author>
<author>
<name sortKey="Takahashi, Tadayuki" uniqKey="Takahashi T">Tadayuki Takahashi</name>
</author>
<author>
<name sortKey="Nakano, Takashi" uniqKey="Nakano T">Takashi Nakano</name>
</author>
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<date when="2013">2013</date>
<idno type="doi">10.1148/radiol.13121194</idno>
<idno type="RBID">pubmed:23418002</idno>
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<term>Animals</term>
<term>Cadmium Compounds (chemistry)</term>
<term>Citrates (chemistry)</term>
<term>Copper (chemistry)</term>
<term>Equipment Design</term>
<term>Fluorodeoxyglucose F18 (chemistry)</term>
<term>Gallium (chemistry)</term>
<term>Gallium Radioisotopes (chemistry)</term>
<term>Gamma Cameras</term>
<term>Imaging, Three-Dimensional</term>
<term>Indium (chemistry)</term>
<term>Iodine Radioisotopes (chemistry)</term>
<term>Pets</term>
<term>Radiopharmaceuticals (chemistry)</term>
<term>Rats</term>
<term>Rats, Wistar</term>
<term>Silicon (chemistry)</term>
<term>Tellurium (chemistry)</term>
<term>Tomography, Emission-Computed, Single-Photon</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en">
<term>Cadmium Compounds</term>
<term>Citrates</term>
<term>Copper</term>
<term>Fluorodeoxyglucose F18</term>
<term>Gallium</term>
<term>Gallium Radioisotopes</term>
<term>Indium</term>
<term>Iodine Radioisotopes</term>
<term>Radiopharmaceuticals</term>
<term>Silicon</term>
<term>Tellurium</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Animals</term>
<term>Equipment Design</term>
<term>Gamma Cameras</term>
<term>Imaging, Three-Dimensional</term>
<term>Pets</term>
<term>Rats</term>
<term>Rats, Wistar</term>
<term>Tomography, Emission-Computed, Single-Photon</term>
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<front>
<div type="abstract" xml:lang="en">To develop a silicon (Si) and cadmium telluride (CdTe) imaging Compton camera for biomedical application on the basis of technologies used for astrophysical observation and to test its capacity to perform three-dimensional (3D) imaging.</div>
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<pubmed>
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<PMID Version="1">23418002</PMID>
<DateCreated>
<Year>2013</Year>
<Month>05</Month>
<Day>24</Day>
</DateCreated>
<DateCompleted>
<Year>2013</Year>
<Month>08</Month>
<Day>09</Day>
</DateCompleted>
<DateRevised>
<Year>2013</Year>
<Month>11</Month>
<Day>21</Day>
</DateRevised>
<Article PubModel="Print-Electronic">
<Journal>
<ISSN IssnType="Electronic">1527-1315</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>267</Volume>
<Issue>3</Issue>
<PubDate>
<Year>2013</Year>
<Month>Jun</Month>
</PubDate>
</JournalIssue>
<Title>Radiology</Title>
<ISOAbbreviation>Radiology</ISOAbbreviation>
</Journal>
<ArticleTitle>Three-dimensional and multienergy gamma-ray simultaneous imaging by using a Si/CdTe Compton camera.</ArticleTitle>
<Pagination>
<MedlinePgn>941-7</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1148/radiol.13121194</ELocationID>
<Abstract>
<AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">To develop a silicon (Si) and cadmium telluride (CdTe) imaging Compton camera for biomedical application on the basis of technologies used for astrophysical observation and to test its capacity to perform three-dimensional (3D) imaging.</AbstractText>
<AbstractText Label="MATERIALS AND METHODS" NlmCategory="METHODS">All animal experiments were performed according to the Animal Care and Experimentation Committee (Gunma University, Maebashi, Japan). Flourine 18 fluorodeoxyglucose (FDG), iodine 131 ((131)I) methylnorcholestenol, and gallium 67 ((67)Ga) citrate, separately compacted into micro tubes, were inserted subcutaneously into a Wistar rat, and the distribution of the radioisotope compounds was determined with 3D imaging by using the Compton camera after the rat was sacrificed (ex vivo model). In a separate experiment, indium 111((111)In) chloride and (131)I-methylnorcholestenol were injected into a rat intravenously, and copper 64 ((64)Cu) chloride was administered into the stomach orally just before imaging. The isotope distributions were determined with 3D imaging after sacrifice by means of the list-mode-expectation-maximizing-maximum-likelihood method.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The Si/CdTe Compton camera demonstrated its 3D multinuclear imaging capability by separating out the distributions of FDG, (131)I-methylnorcholestenol, and (67)Ga-citrate clearly in a test-tube-implanted ex vivo model. In the more physiologic model with tail vein injection prior to sacrifice, the distributions of (131)I-methylnorcholestenol and (64)Cu-chloride were demonstrated with 3D imaging, and the difference in distribution of the two isotopes was successfully imaged although the accumulation on the image of (111)In-chloride was difficult to visualize because of blurring at the low-energy region.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">The Si/CdTe Compton camera clearly resolved the distribution of multiple isotopes in 3D imaging and simultaneously in the ex vivo model.</AbstractText>
</Abstract>
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<LastName>Suzuki</LastName>
<ForeName>Yoshiyuki</ForeName>
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<Affiliation>Department of Radiation Oncology, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511, Japan.</Affiliation>
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<Language>eng</Language>
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<PublicationType>Research Support, Non-U.S. Gov't</PublicationType>
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<Year>2013</Year>
<Month>02</Month>
<Day>15</Day>
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<Country>United States</Country>
<MedlineTA>Radiology</MedlineTA>
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<ISSNLinking>0033-8419</ISSNLinking>
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<Chemical>
<RegistryNumber>0</RegistryNumber>
<NameOfSubstance>Cadmium Compounds</NameOfSubstance>
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<DescriptorName MajorTopicYN="N">Tellurium</DescriptorName>
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